Miller predicted the 49ers to miss the playoffs, saying it looks like a “lost year” for the 49ers. Miller pointed to the ...

San Francisco 49ers wide receiver Brandon Aiyuk had to be carted to the locker room during the 49ers' Week 7 game against the Kansas City Chiefs. The wideout had made his second catch of the game ...

Christian McCaffrey is set to make his season debut for the San Francisco against the Tampa Bay Buccaneers on Sunday. How ...

At an up-and-down 3-4, the reigning NFC champion San Francisco 49ers can't be reliably counted on as a bona fide contender.

San Francisco 49ers wide receiver Brandon Aiyuk posted a video to his YouTube channel on Monday, providing an update on his ...

Brandon Aiyuk has been placed on injured reserve, dealing a major blow to the 49ers as they navigate key injuries.

San Francisco 49ers wide receiver Brandon Aiyuk might have suffered a significant injury in Sunday's loss to the Kansas City ...

A rough season for Brandon Aiyuk just got worse. The star San Francisco 49ers receiver, who held out until getting a $120 million extension before the start of the season, was carted off with a ...

San Francisco 49ers standout wide receiver Brandon Aiyuk tore his ACL and MCL in Sunday's loss to the Kansas City Chiefs and ...

San Francisco 49ers head coach Kyle Shanahan relayed what the organization feels star receiver Brandon Aiyuk might have after being carted off the field against the Kansas City Chiefs on Sunday.

The San Francisco 49ers lost standout receivers Brandon Aiyuk and Deebo Samuel during Sunday's 28-18 loss to the visiting ...

Latest injury update on Brandon Aiyuk, who injured his leg and was carted off during the 49ers' game against the Chiefs on ...