Jaguars fans remember the last time Flacco suited up against Jacksonville, in Week 14 of 2023 for Cleveland with starting quarterback Deshaun Watson out due to a season-ending shoulder injury. Flacco threw for 311 yards, three touchdowns and one interception in the Browns’ 31-27 victory.

Indianapolis Colts quarterback Anthony Richardson's status for Sunday's game has been downgraded to doubtful, making it unlikely the second-year player suits up against the Jacksonville Jaguars. Richardson suffered an oblique injury after a high-speed collision with a defender in last week's 27-24 win over the Pittsburgh Steelers.

A banged-up Colts team is likely going to have to break a decade-long drought in Jacksonville without its starting quarterback, in addition to its starting center, best defensive lineman, two starting defensive ends and its best cornerback.