Monday's match marked just the second time Keys and Zarazúa faced off. Keys won the first encounter, beating Zarazúa at the 2024 French Open. With her win Monday, Zarazúa evened the their head-to-head record.

Australian Open champion Madison Keys has been undone by 89 unforced errors during a 6-7 (10), 7-6 (3), 7-5 loss to Mexico’s Renata Zarazua in the first round of the U.S. Open

NEW YORK — Australian Open champion Madison Keys is out of the U.S. Open in the first round. Renata Zarazúa, the world No. 82 from Mexico, came from a set and 3-0 down to stun the No. 6 seed 6-7 (10), 7-6 (3), 7-5 in bright sunlight on Arthur Ashe Stadium. Zarazúa also became the first Mexican woman to ever beat a top-10 opponent at the U.S. Open.