Nikki Glaser prepared heavily for her Golden Globes hosting gig. She expressed hesitation over telling a Diddy joke, but went for it anyway.

Nikki Glaser pulled no punches as she kicked off the Golden Globes in Los Angeles, telling the A-List audience that the award show was “Ozempic’s biggest night.” The 40-year-old comedian, who is known for her dark and often offensive brand of humor,

While this is her first time hosting the Globes, the comedian is no stranger to commanding an audience: Glaser went viral late last year for her performance on Netflix’s The Roast of Tom Brady, and she has been performing stand-up comedy for over two decades.