Few functional groups are as popular in synthesis as the carbonyl group. Composed of an oxygen molecule doubly bonded to carbon, the carbonyl welcomes reaction with all types of nucleophiles.

Enantioselective α-alkylation of carbonyl is considered as one of the most important processes for asymmetric synthesis. Common alkylation agents, that is, alkyl halides, are notorious substrates for ...

Histones are crosslinked with DNA (histone-DPC) following formaldehyde exposure, leading to the malfunction of cellular processes such as transcription. A team of researchers at Nagoya University in ...

Synthetic biologists have engineered bacteria to prevent the microbes from reducing aromatic aldehydes, allowing the cells to synthesize flavorants such as vanillin and a precursor to the ...

Strecker synthesis is one of several means of producing α-amino acids. α-amino acids are molecules, which contain an amine and carboxylic group that are separated by a single carbon (the α-carbon).

Researchers have discovered the connection between aldehydes, organic compounds produced by cells as part of metabolic processes, and rapid aging. Their findings indicate a potential treatment for ...