RSD1235 is a novel, frequency-dependent sodium and early-activating potassium-channel blocker under joint development by Cardiome (Vancouver, Canada) and its partner, Astellas Pharma US (Deerfield, ...

Human ether-à-go-go related gene (hERG), KCNQ and Kv1.2 channels were expressed in CHO cells. The delayed rectifier potassium current (I K) was recorded from dissociated hippocampal pyramidal neurons ...

Atrial fibrillation is the most common type of cardiac arrhythmia, and is a common cause of stroke and heart failure. Currently, there is a major unmet need for drugs that are capable of successfully ...

Background: Of the antiarrhythmic agents currently marketed in Canada, 5 are commonly used to treat atrial fibrillation (AF). The impact of contraindications, warnings and precautions for the use of ...

Norpace CR is a Type 1 antiarrhythmic drug indicated for the treatment of documented ventricular arrhythmias. Pfizer has issued an update regarding the availability of Norpace CR (disopyramide ...

The batch was distributed between August 14, 2018 and September 5, 2018. Nexterone is a prescription antiarrhythmic agent indicated for initiation of treatment and prophylaxis of frequently recurring ...