Aptamers—folded oligonucleotides designed to bind a ligand of interest—are often used to make biosensors. But finding high-affinity, selective aptamers for very small molecules such as simple sugars ...

Aptamers—folded oligonucleotides designed to bind a ligand of interest—are often used to make biosensors. But finding high-affinity, selective aptamers for very small molecules such as simple sugars ...

Since its emergence at the end of 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected over 526 million worldwide and caused over 6.28 million deaths. SARS-CoV-2 ...

This schematic shows the secondary structure of two aptamers. The complex shapes formed by base pairing (black lines connecting G-C and A-T bases) allow aptamers to bind their targets with high ...

Aptamers, nucleic acids capable of selectively binding to viruses, proteins, ions, small molecules, and various other targets, are garnering attention in drug development as potential antibody ...

Aptamers can measure blood levels of the amino acid leucine, which could be applied to newborn screening for maple syrup urine disease. Credit: Milan Stojanovic Aptamers can measure blood levels of ...

Drug-carrying DNA aptamers can deliver a one-two punch to leukemia by precisely targeting the elusive cancer stem cells that seed cancer relapses, researchers report. The aptamers -- short ...

Often described as synthetic antibodies, aptamers are single-stranded DNA or RNA molecules that fold into secondary structures which can bind to target molecules with high affinity and specificity. In ...

Today, biochemical methods are one of the most precise ways to confirm a diagnosis. When it comes to biochemical diagnostics of cardiovascular diseases, medical professionals evaluate the level of ...

The amino acid arginine may have played a more important role than previously thought in the chemical origins of life Life as we know it originated roughly 3.5 to 4 billion years ago in the form of a ...