Mitochondria are central hubs for cellular stress adaptation, with their function integrated with both apoptosis and autophagy pathways that determine cell fate. Alterations in mitochondrial ...

Autophagy is essentially the 'rubbish collection' of our cells. If there are problems in this process, which is so important for our health, diseases such as Parkinson's can result. In their latest ...

Findings underpin the scientific rationale for Anavex’s targeted autophagy approach with orally administered blarcamesine Convergence of impaired autophagy and synaptic dysfunction across ...

Autophagy is indispensable for maintaining hepatocyte integrity, metabolic homeostasis, and survival. While several autophagy-related proteins have been studied in hepatic physiology, the specific ...

Autophagy is a natural, conserved process where cells degrade and recycle their own components, including damaged proteins and organelles. This targeted removal is orchestrated by cargo receptors, ...

Tick-borne encephalitis virus, known as TBEV, hijacks the internal membrane machinery of host cells to build hidden factories ...

Memorial Hospital for Cancer and Allied Diseases and the Memorial Sloan Kettering Cancer Center have disclosed 4-aminoquinoline inhibitors of the autophagy-lysosomal pathway (ALP) intended for the ...

Modern lifestyles and dietary changes have significantly increased the consumption of high-fat foods, contributing to a steep rise in the prevalence of obesity, diabetes, and metabolic disorders.