The 2022 Nobel Prize in chemistry was awarded to scientists Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless for their development of click chemistry and bioorthogonal chemistry. These ...
Click chemistry is a strategy for building molecules by snapping together two complementary chemical handles in a single, dependable step. Rather than relying on long multi-step syntheses, it uses a ...
The advancement of bioorthogonal bond-breaking chemistry requires precise spatiotemporal control over chemical reactions. In this study, we introduce a click-release strategy based on the reaction ...
A team of researchers writing in the journal Angewandte Chemie has developed a bioorthogonal molecular system for the targeted introduction of nitrite ions into cells. Their system releases nitrite ...
Please provide your email address to receive an email when new articles are posted on . It’s not often that a 2 a.m. phone call marks the highlight of someone’s career. That call notified Bertozzi, ...
This year’s Nobel Prize in Chemistry has been awarded for the development of a simple and reliable method for efficiently connecting two molecules that can even take place inside living cells. It has ...
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