Riley Children’s used deceased donor stem cells to treat a teen with leukemia, a method that may reduce wait times and expand ...

While research has uncovered many details about how blood cells function within bone marrow, the work of other cells existing in that space has remained a relative mystery. Now, researchers from the ...

Each year, doctors treat more than 6 million bone fractures in the United States. And while it takes only a few seconds for a ...

Osteoblasts are specialized bone cells responsible for building and regenerating bone tissue. Researchers at Leipzig University have shown that a specific receptor plays a key role in the strength of ...

Bone health relies on a balance between osteoblasts (builders) and osteoclasts (recyclers). Peak bone mass occurs in early adulthood; deficiencies during this window amplify fracture risks later in ...

In a study published in Cell Research, researchers have identified a fibrous-layer resident subpopulation of P-SSCs labeled by Angptl7. They found that these cells are crucial for bone fracture repair ...

Bone is a vital organ that is constantly remodeled throughout the lifetime 1. Bone consists of cortical bone that surrounds a central bone marrow cavity and trabecular bone that traverses a bone ...

Bone is a common site for metastasis of solid cancers, but histological and molecular features of bone metastases are not well understood. In a new study published in Cell Genomics, researchers at ...

In a discovery that could reshape approaches to regenerative medicine and bone repair, researchers have found that human stem cells can be prompted to begin turning into bone cells simply by squeezing ...

Bone tissue is generally resilient and can self-heal, but critical-size defects (CSDs) with complex geometries cannot be repaired without clinical intervention. Customized scaffolds developed using ...

Bone tissue engineering (BTE) has emerged as a critical solution for repairing large bone defects caused by trauma, infection ...

Researchers recently developed a bone marrow model to study how the body generates cells. Interestingly, this model is the first of its kind to be developed entirely from human cells. Not only can ...