The discovery of a family with sequence similarity 102 member A (Fam102a) protein as a novel bone remodeling factor that regulates both osteoclast and osteoblast differentiation can aid the ...

Researchers used advanced imaging to uncover early molecular changes in bone that may enable earlier diagnosis of ...

Sustained hypoxia affects orthodontic tooth movement (OTM) by altering osteoclast and osteoblast differentiation, report researchers from Institute of Science Tokyo, Japan. Hypoxic conditions resulted ...

This diagram illustrates the role of macrophage ATF6 in orthodontic tooth movement. When corticotomy is applied, monocytes are recruited to the bone, where they differentiate into pro-inflammatory ...

It’s common to think of your bones as solid and unchanging, but they’re composed of living tissue constantly in flux. Consider: Every year, 15% of your spine and 5% of your hips are replaced with new ...

Osteoarthritis often goes undetected until cartilage damage is advanced, limiting treatment options. A new study shows that molecular changes in subchondral bone occur earlier and can signal disease ...

Orthodontic tooth movement is fundamentally driven by the application of controlled mechanical forces to reposition teeth within the alveolar process. This movement is intrinsically linked to alveolar ...

For years, clinicians have noticed that people living with major depression often show unexpectedly fragile bones. What ...

Fam102a-Rbpjl axis in osteoblast differentiation reveals significant insights into bone remodeling and may aid the development of therapeutic strategies. Bones are the living tissue on which the human ...