The hippocampus follows a "tabula plena" model, starting with dense, random connections that are pruned into an efficient ...

Problems with the brain’s ability to ‘prune’ itself of unnecessary connections may underlie a wide range of mental health disorders that begin during adolescence, according to research published today ...

A new study from Austrian researchers suggests the brain begins life with an overly dense and disorganised network of ...

Early in life, neural networks in the brain's memory center are highly connected, and they are only later refined into ...

Full at birth: Researchers found newborn mouse hippocampal networks are densely and randomly connected, not empty as previously thought. Pruning with age: Connections become sparser and more organized ...

Adolescence is widely thought to be a time when the brain trims away excess neural connections, refining circuits through synaptic pruning. New research now suggests this view may be incomplete.

Many disparate conditions, such as depression, phobias and attention deficit hyperactivity disorder (ADHD), may have the same underlying cause: a delay in “pruning”, a process in which unneeded ...

The brain’s memory center may begin life more like a crowded web than an empty canvas. Researchers discovered that early ...

If you scroll through TikTok or Instagram long enough, you’ll inevitably stumble across the line: “Your frontal lobe isn’t fully developed yet.” It’s become neuroscience’s go-to explanation for bad ...

In the Alzheimer’s disease brain, synaptic loss correlates with cognitive decline, and is considered a sign of disease progression. But is synaptic loss always bad? Provocative new data from several ...

Early childhood is a critical period for brain development, which is important for boosting cognition and mental well-being. Good brain health at this age is directly linked to better mental heath, ...