Proteins that are no longer needed, defective, or potentially harmful are labeled with a molecular "tag" and dismantled in ...

Abnormal cell proliferation is a major hallmark of cancer. Several proteins are involved in the cell cycle, and most of these regulate the positive or negative control of cyclin-dependent kinases.

A research group led by Professor Michael Glickman, dean of Technion's Faculty of Biology, has uncovered a key mechanism in ...

The awe-inspiring process of cell division can turn a fertilized egg into a baby – or a cancerous cell into a malignant tumor. With so much at stake, nature keeps it tightly controlled in a process ...

Department of Pharmaceutical Chemistry and the Institute for Neurodegenerative Diseases, University of California San Francisco, San Francisco, United States ...

Caulobacter crescentus provides a robust model for exploring the complexities of bacterial cell cycle regulation. Its unique life cycle, typified by an asymmetric division that produces distinct ...

Preclinical AML studies showed palbociclib plus venetoclax produced stronger, more durable anti‑leukemia activity than venetoclax alone and may overcome resistance.

Life’s most indispensable molecules are not the serene, unchanging fixtures they might appear to be. Even the proteins that ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

UCSF scientists discover that multiciliated cells adapt the well-known process of cell division to make hundreds of cilia. The awe-inspiring process of cell division can turn a fertilized egg into a ...