Cytotoxicity is a broad term that refers to the negative effects of chemical or environmental changes on cell health. Cells exposed to a cytotoxic stimulus may lose metabolic activity, experience ...

Medical device manufacturers use cytotoxicity testing to help prove that devices that come into contact with the human body are biocompatible. Testing results are critical for gaining market access, ...

When the body encounters infection or cancer, cytotoxic T lymphocytes attach to the affected cell and form the immune synapse ...

Scientists use multi-day live cell assays to monitor cell growth, viability, and cytotoxicity when evaluating the effects of drug treatment. However, maintaining consistent cell health over time ...

Cytotoxic T lymphocytes are the body's specialized "killer" cells, precisely eliminating infected or cancerous cells. Their ...

Explore luminescence screening assays for drug discovery, including luciferase and ATP assays. Learn the principles, formats, advantages, and limitations.

Potency assay development uses DoE and QbD to improve accuracy, consistency, and regulatory readiness in biologics testing.

An integrated suite of bioassays provides a coherent workflow to track antibody Fc effector activity across every stage of mAb drug development Potency assays that fail during tech transfer or ...

Phase 1 study of LB1410, a bivalent TIM-3/PD-1 bispecific antibody, in patients with advanced solid tumors or lymphoma. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This ...

Most cytotoxicity test “failures” trace back to controllable factors like device materials, sterilant or other chemical residues, or physicochemical characteristics of the extract - which means ...