One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published in Nature.

Researchers have made a significant advancement toward understanding how the human genome is organized inside a single cell. This knowledge is crucial for analyzing how DNA structure influences gene ...

The genetic heritage is not a simple, static list inside the cell nucleus. It unfolds into a dynamic architecture whose ...

Despite being densely packed to fit into the nucleus, chromosomes storing our genetic information are always in motion. This allows specific regions to come into contact and thereby activate a gene. A ...

Almost like a moon in a planet, the exclusome (yellow- green dot) lies in the cytoplasm near the nucleus (blue). Even the remarkably familiar can sometimes yield new discoveries: researchers at ETH ...

Researchers at Rice University are making strides in understanding how chromosome structures change throughout the cell's life cycle. Their study on motorized processes that actively influence the ...

Around one million individuals worldwide become infected with HIV, the virus that causes AIDS, each year. To replicate and spread the infection, the virus must smuggle its genetic material into the ...

In order for HIV to replicate, the viral genome must enter into the cell nucleus and integrate into the host cell chromosome. Previous work suggests that the entry proceeds through nuclear pore ...

Many species undergo programmed DNA elimination, a process where specific parts of the genome found in the original sperm and egg cells are removed from the cells of the developing body. Different ...

Oregon scientists used human skin cells to create fertilizable eggs, a step in the quest to develop lab-grown eggs or sperm to one day help people conceive. But the experiment resulted in ...