When cells expire, they leave behind an activity log of sorts: RNA expelled into blood plasma that reveals changes in gene expression, cellular signaling, tissue injury and other biological processes.

RNA can act as an intermediary between the genome and the cell; active genes are transcribed into messenger RNA molecules, for example. While RNA can perform a variety of crucial functions, it is also ...

Somewhere in the body of a patient, a small clump of cells, growing undetected, has begun to form a tumor. It has yet to cause pain or visible symptoms of illness. Several months from now, or perhaps ...

Biomarker studies increasingly utilize biofluids as an attractive source of molecules reflecting human health and disease states. Referred to as liquid biopsies, they have the advantage over tissue ...

When a tumor starts to grow in the body, small bits of its genetic material may break away and float off into the bloodstream. This so-called cell free DNA can be used to identify cancer at very early ...

University of Chicago researchers have developed a liquid biopsy test based on modification patterns in microbiome-derived cell-free RNA that predicts colorectal cancer (CRC) with greater accuracy ...

RNA is expelled from cells via cell death or active release, and can then find its way into blood plasma. A Cornell University-led collaboration has developed machine learning models that use these ...

Children born before 37 weeks of gestation have a considerably increased risk of dying before they reach the age of five. Predicting the risk of preterm birth (PTB) and hence implementing preventive ...

Cell-free nucleic acids, encompassing both DNA and RNA fragments released into the maternal circulation, provide a minimally invasive window onto placental and foetal health. Originating from ...

Stanford Medicine researchers have developed a blood test capable of detecting cancers, the ways cancer resists treatments and tissue injury caused by non-cancerous conditions. The new test analyzes ...

Galit Meshulam-Simon is the associate director of Commercial Applications at Elegen. COVID-19 brought messenger RNA (mRNA) into the global spotlight, demonstrating its speed, flexibility, and efficacy ...