In 2005, few neuroscientists would have bet that electron microscopy could map entire neural circuits in three dimensions. The technique was slow and cumbersome, offering only thin slices of brain ...

Connectomics, a rapidly evolving field in neuroscience, is transforming our understanding of the brain’s intricate network of neural connections. By mapping these complex pathways, scientists aim to ...

Our brain is a complex organ. Billions of nerve cells are wired in an intricate network, constantly processing signals, enabling us to recall memories or to move our bodies. Making sense of this ...

Compared to traditional electron microscopy, it lowers both cost and technical barriers. "At the current resolution of the images—20 nanometers—synapses can already be identified. We managed to ...

Electron microscope (EM) has revolutionized our ability to visualize the intricate details inside cells. The advancement to 3D electron microscopy, known as volume EM (vEM), has further expanded this ...

The mysteries of the brain have captivated scientists for more than 100 years, most notably illustrated in the detailed drawings of neuroanatomist Santiago Ramón y Cajal. These drawings and his ...

Microscopy is an imaging technique that enables us to see a world that would otherwise be invisible to us. Once upon a time, visualizing cells, microbes and other entities not perceptible to the naked ...

Electron microscopy is a powerful technique that provides high-resolution images by focusing a beam of electrons to reveal fine structural details in biological and material specimens. 2 Because ...

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Electron microscope (EM) has revolutionised our ability to visualise the intricate details inside cells. The advancement to 3D electron microcopy, known as volume EM (vEM), has further expanded this ...