MIT engineers develop a new system for precise control of synthetic gene expression, potentially advancing gene therapy.

Engineers have created DIAL, a modular system that precisely sets and edits protein levels in synthetic gene circuits. By ...

The research field of 'cellular IRESes' lay dormant for decades, as there was no uniform standard of reliable methods for the clear characterization of these starting points for the ribosome-mediated ...

Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the ...

A figure from the paper illustates a key finding of "compromised compartmentalization": chromatin that was locking genes down in health became more open in Alzheimer's, while chromatin that was open ...

Torino is a computational workflow that uses biobank-scale RNA-seq data to decode transcript structures and expression levels from read coverage alone.