Drugs made of mRNA have the potential to transform medicine—if only they could get into cells in one piece. Now, University ...

Two separate laboratory breakthroughs have produced RNA molecules that can build copies of themselves or assemble functional structures without any help from proteins or DNA. These results offer the ...

These random molecules were fed a collection of three-base-long RNAs, each linked to a chemical tag. The idea was that if a molecule is capable of ligating one of these short RNA fragments to itself, ...

Researchers identified how the poxvirus protein VITF-3 forms a molecular ring that clamps onto DNA with viral RNA polymerase, ...

Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene ...

Researchers at the MRC Laboratory of Molecular Biology in Cambridge have discovered a ribozyme that is shockingly small, yet ...

Researchers developed C28, an engineered polymerase that efficiently synthesizes RNA at near-natural speeds with high accuracy. Created through directed evolution, the enzyme also performs reverse ...

Different DNA Structures Nucleate the Folding of Proteins to form specific complexes that modulate the readout of ...