A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem ...

Gene regulatory networks (GRNs) depict the regulatory mechanisms of genes within cellular systems as a network, offering vital insights for understanding cell processes and molecular interactions that ...

LysR-type transcriptional regulators (LTTRs) constitute one of the most ubiquitous and versatile families of proteins in prokaryotes, playing a pivotal role in modulating gene expression in response ...

Gene regulation is the process by which cells control the expression of their genes, determining when, where, and to what extent each gene is expressed. It is a fundamental mechanism that allows cells ...

Our genes contain all the instructions our body needs to function, but their expression must be finely regulated to guarantee that each cell performs its role optimally. This is where DNA and RNA ...

Origin-recognition complex, or ORC, plays an unexpectedly broad role in the regulation of human cell gene expression, according to a study in the journal Cell Reports. This is the first detailed study ...

A newly discovered code within DNA -- coined 'spatial grammar' -- holds a key to understanding how gene activity is encoded in the human genome. This breakthrough finding revealed a long-postulated ...

Plant bioengineering—in which plant genes are modified to include desirable characteristics—is the key to solutions for problems concerning crop resilience and food security. Elements like gene ...