Researchers showed how what appears to be a tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell. The work, published as two papers in Nature ...

Life begins with a quiet but precise choreography inside the nucleus. For decades, scientists believed that a newly fertilized egg started in disorder, its DNA loosely arranged and waiting for ...

Two new studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands of genes ...

Scientists have uncovered a surprising secret about our DNA: it’s not a static blueprint, but a constantly shifting, folding ...

Before cells can divide by mitosis, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Scientists have until now ...

The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible to the cellular machinery that works to express the right genes at the ...

DNA might be too small to see with the unaided eye, but it packs our cells in shocking quantities: More than six and a half feet of DNA lies within every cellular nucleus. It squeezes into such a ...

Fox Chase researchers use 3D genomic testing to improve lymphoma and sarcoma diagnosis and treatment by revealing tumor cell ...

Gene regulation and chromatin dynamics constitute central themes in modern molecular biology, governing how the genetic blueprint is accessed and utilised during development, differentiation and ...

Before cells can divide, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Until now, scientists had believed that ...

A study in the Chinese Journal of Natural Medicines reports the first high-resolution structure of the major G-quadruplex in the TMPRSS2 promoter and shows how berberine binds and stabilizes it, ...