Primordial germ cell-like cells (PGCLCs), generated in vitro from the stem cells of rats, undergo gametogenesis in vivo and yield normal rat offspring, a new study demonstrates. While the birth of ...

Primordial germ cells (PGCs), the precursors of sperm and eggs, are generated during early embryo development. However, the genes involved in PGC specification in rats are not well understood. In this ...

Rat sperm cells generated from stem cells in the lab have been used to produce fertile offspring for the first time. The approach could be adapted to rescue endangered rodents and may help to inform ...

Germ cell production in genetically modified hybrid animals is now a reality rather than science fiction, as recently demonstrated by researchers at ETH Zurich. Stem cell biologist Ori Bar-Nur, PhD, ...