Robust pancreatic tumor suppression by a novel combination treatment with anti-PD-1 immune checkpoint antibody and stroma modifying RNA oligonucleotide STNM01 in mice. This is an ASCO Meeting Abstract ...
A research team led by Prof. ZHU Shu from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences (CAS) illustrated the role of Gasdermin D (GSDMD) protein in ...
from left) Prof. Florian I. Schmidt and Lisa Schiffelers use nanobodies to clarify the formation of pores by gasdermin D in cell membranes. The formation of pores by a particular protein, gasdermin D, ...
Atherosclerosis is a chronic inflammatory condition and a known risk for the development of cardiovascular diseases. In animal models of atherosclerosis, macrophage pyroptosis is linked to the ...