The Diels-Alder reaction is a classic transformation that typically marries a diene (with four π electrons) and an alkene (with two π electrons) to form a six-membered ring—it’s known as a [4+2] ...

For the synthesis of optically active compounds, chiral catalysts have attracted much attention because large quantities of optically active molecules can be prepared from a small amount of a chiral ...

Pericyclic reactions, which involve concerted electron movement and a cyclic transition state, have long been a part of the synthetic chemist’s tool box. But finding enzymes that catalyze such ...