Understanding how major histocompatibility complex class (MHC) molecules and peptides interact within the immune system is crucial for the advancement of biological sciences and medicine. A better ...

The major histocompatibility complex class-I (MHC-I) peptideloading complex (PLC) is a cornerstone of the human adaptive immune system, being responsible for processing antigens that allow killer T ...

The repertoire of αβ T cell antigen receptors (TCRs) on mature T cells is selected in the thymus where it is rendered both self-tolerant and restricted to the recognition of major histocompatibility ...

Study introduces TRACeR-I, a protein platform with broad HLA compatibility, paving the way for advanced immune response engineering and disease-specific targeting. Study: Targeting peptide antigens ...

Class I major histocompatibility complex (MHC-I) proteins play an essential role in the immune system of all jawed vertebrates. The MHC-I displays peptide fragments of proteins from within the cell on ...

The human leukocyte antigens (HLA-I) are multi-subunit complexes that localize to the cell surface and present bound peptides to nearby immune cells. The study of these HLA peptide-presenting ...