Cellular phase separation may play a previously underappreciated role in regulating kinase activity, offering therapeutic ...

The cell cycle—growth, reproduction, and death—is regulated by a complex combination of genes, turned on and off throughout a cell’s life. Enzymes called protein kinases manage this cycle, which is ...

Within the past decade, biologists have discovered that one strategy cells use to keep their contents organized is a ...

Dedifferentiated liposarcoma (DDLS) is a rare and aggressive soft tissue cancer with few effective treatment options. But now ...

Analyzing aberrantly methylated collagen genes in colorectal adenocarcinoma. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract does not include a full text component.

Chemotherapy drugs that target a common mutation in colorectal cancer rapidly lose efficacy in patients, leading to relapse.

Enzymes known as kinases play a critical role in cell growth, metabolism and signaling in a multitude of organisms across the tree of life—from algae to helminths to mammals. Now, scientists have ...