A new comprehensive atlas of cells fills gaps in knowledge on how different cells in the intestine act together to drive celiac disease, potentially opening new avenues for future therapeutic ...

The mammary gland is remarkable in its capacity to undergo multiple cycles of growth and regression during reproductive years. Mammary gland remodeling is largely driven by hormonal cues that guide ...

Alterations in intestinal structure, mechanics and physiology underlie acute and chronic intestinal conditions, many of which are influenced by dysregulation of microbiome, peristalsis, stroma or ...

Coeliac disease is a long-term autoimmune condition that affects about 0.5% to 1% of people. A new published collaborative report from scientists at Children’s Health Ireland (CHI) , Johnson & Johnson ...

Intestinal tuft cells divide to make new cells when immunological cues trigger them. Additionally, in contrast to progenitor- and stem cells, tuft cells can survive severe injury such as irradiation ...

New evidence shows that human M cells act as fully fledged antigen-presenting cells, processing and presenting gluten peptides through a dendritic cell-like pathway that may shape early coeliac ...

Animal models have enabled us to learn an incredible amount of new information about human biology, health, and disease. But these animals can't always serve as a reliable example of the human body.

Researchers have discovered a way to help aging intestines heal themselves using CAR T-cell therapy. By targeting senescent cells that build up over time, the treatment boosted gut regeneration, ...

In a recent study published in the journal Frontiers in Immunology, researchers investigate the impact of dietary antigens in regulating small intestinal tumors. Despite being the most common type of ...

Intestinal tuft cells divide to make new cells when immunological cues trigger them. Additionally, in contrast to progenitor- and stem cells, tuft cells can survive severe injury such as irradiation ...