Can lithium’s effect on daily activity patterns reveal who will benefit from treatment? A six-week trial finds circadian shifts emerge early, before mood improves, hinting at a biological clue to ...

Lithium is the lightest metal—indeed, it can float on water—with a variety of uses in the modern world, including as the negative electrode in lithium batteries, a coolant inside nuclear power plants, ...

Bipolar disorder, a neuropsychiatric condition that includes manic and depressive episodes, affects about 1% of the population and is strongly influenced by genetics. About half of patients respond ...

Changes Clinical Practice: Based on this large trial, lithium alone or a lithium-valproate combination should be used as first-line maintenance treatment for bipolar affective disorder type I instead ...

Since 1949, lithium has been a mainstay for treating bipolar disorder (BD), a mental health condition marked by extreme mood swings. But scientists still don't have a clear understanding of how the ...

Six predictors could help determine the amount of lithium needed to treat patients with bipolar disorder, according to a large study led by researchers at Karolinska Institutet in Sweden. The study, ...

Low doses in mice have can clear up proteins associated with Alzheimer’s disease and restore memory. Human trials are the next step. Lithium has long been a standard treatment in bipolar disorder, but ...

Compared with lithium, valproate, olanzapine, quetiapine, and risperidone generally exhibited a lower likelihood of thyroid dysfunction. HealthDay News — Lithium is associated with an increased risk ...

Lithium carbonate and valproate sodium are each recommended as monotherapy for preventing relapses in patients with bipolar disorder and are sometimes used in combination. However, combination therapy ...

Since 1949, lithium has been a mainstay for treating bipolar disorder (BD), a mental health condition marked by extreme mood swings. But scientists still don't have a clear understanding of how the ...