Mood stabilizers protect against suicide and all-cause mortality in patients with bipolar disorder (BD), including natural mortality, with lithium emerging as the most protective agent, new research ...

Can lithium’s effect on daily activity patterns reveal who will benefit from treatment? A six-week trial finds circadian shifts emerge early, before mood improves, hinting at a biological clue to ...

A study this week in the journal Nature found that the loss of lithium, a naturally occurring element in the brain, could be an early sign of Alzheimer’s and a powerful driver of the disease, which ...

Long-term mood stabilizer use in bipolar disorder Mixed and psychotic features and comorbid anxiety disorder were also associated with poor treatment response. About one-third of patients receiving ...

Recent lithium and valproate use was associated with a 34%-46% lower risk for suicide in patients with schizophrenia or bipolar disorder (BD), investigators leading a large cohort study reported.

Researchers from the University of Adelaide are hopeful a recent biological discovery could lead to the precision treatment of bipolar disorder (BD). About 2.2% of the Australian population has a form ...

Source: Francesco Mocellin / Used with permission Interest in lithium has been renewed in recent years, not only as a classic mood stabilizer for bipolar illness but also as a potential low-dose ...

Lithium was associated with a higher risk of thyroid and kidney dysfunction versus non-lithium treatments in bipolar disorder patients. Associations were dose-dependent and serum level cutoffs for ...

A second meta-analysis of antimanic treatments, conducted by Yildiz et al, 6 focused on direct comparisons of individual medications and on effects of classes of medication. Second-generation ...