New research reveals previously unknown ways opioid receptors can function, opening the door to safer pain treatments.

New research could transform how we understand the way opioids affect the brain. Despite significant discussion surrounding the ongoing opioid crisis, current understanding of how opioids function in ...

Experiments reveal that a time-dependent epistatic interaction influences how mice respond to opioids, and that intracellular fibroblast growth factors also influence opioid sensitivity.

Opioid antagonists are medications people can take to treat opioid use disorder. They help by reducing withdrawal symptoms, addressing cravings, and managing overdoses. Doctors prescribe opioid ...

Having a pill that alleviates chronic pain without adverse side effects or the risk of addiction remains an unmet pharmaceutical need for millions of people currently using traditional opioid drugs.

Increasing the levels of chemicals naturally produced in the body called endocannabinoids may thwart the highly addictive nature of opioids such as morphine and oxycodone while maintaining the drugs' ...

Nausea, sweating, and diarrhea are just some of the possible symptoms of opioid withdrawal. How soon those symptoms start and how long they last can vary by person, but the general opioid withdrawal ...