A research project has successfully reproduced the pathogenesis of autosomal dominant polycystic kidney disease (ADPKD) from human iPS cells in vitro. Although cysts derived from renal tubules have ...

Correspondence to Dr Lauren Pringels, Department of Physical and Rehabilitation Medicine, Ghent University Hospital, Ghent, Belgium; Lauren.Pringels{at}UGent.be Despite the high prevalence of tendon ...

Autoimmune gastritis is a chronic progressive inflammatory condition that results in the replacement of the parietal cell mass by atrophic and metaplastic mucosa. A complex interaction of ...

Reviewed by Loren Wissner Greene, MD, MA (Bioethics), Clinical Associate Professor of Medicine, NYU School of Medicine, New York, NY For many years, it has been well known that causes of type 2 ...

Like all forms of cancer, lung cancer is defined by uncontrolled cell division caused by loss of physiological tissue homeostasis and failure of apoptotic cell death mechanisms. Aberrant cell ...

The research in Singh laboratory is broadly focused on the pathophysiology of iron in disorders of the brain and the eye. Current interests in the lab include: Iron cycling in the eye. Pathophysiology ...

A detailed overview of the pathophysiology of diabetes mellitus, covering key mechanisms, disease progression, metabolic ...

Angioedema is basically swelling of the deeper layers of the skin. This is due to accumulation of fluids caused by an allergic reaction. Pathogenesis of the types of angioedema has been studied ...

The main problem or pathology in glaucoma is caused by raised intraocular pressure. It is this raised pressure that compresses and damages the optic nerve. Once the optic nerve is damaged, it fails to ...

What are the lasting effects of COVID-19 on the body? Paul Benson, M.D., Professor and Autopsy Section Head in the Department of Pathology's Division of Anatomic Pathology, was awarded a Researching ...