Using ribosome engineering (RE), researchers from Shinshu University introduced mutations affecting the protein synthesis ...

The discovery of ribosomes dates back to the 1950s, when George Palade first observed dense particles in the cytoplasm of cells using electron microscopy. These particles were later named "ribosomes" ...

The ribosome serves as the essential molecular machine that translates genetic information carried by messenger RNA (mRNA) into functional proteins. Comprised of two distinct subunits, the ribosome ...

Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell makes a copy of DNA, called mRNA. Then, another molecule called a ribosome reads the mRNA, translating it ...

Scientists at the University of California, Santa Cruz, have trapped the ribosome, a protein-building molecular machine essential to all life, in a key transitional state that has long eluded ...

Ribosomes are fundamental molecular machines that translate mRNA sequences into polypeptides, ensuring the proper synthesis of proteins essential to cellular function. However, the fidelity of protein ...

Pool engineering using sequence-optimized ribosomes can significantly improve protein synthesis yields, thus lowering drug manufacturing costs, according to recent research from Northwestern ...

Inside our cells, ribosomes-the tireless “protein factories” of life-have just shown off a new skill they haven’t used in billions of years. A research team led by Professor Joongoo Lee in the ...

To ensure that protein production in our cells runs smoothly, the protein complex NAC slows down the rate of protein synthesis right at the start.

Transcription and translation are processes a cell uses to make all proteins the body needs to function from information stored in the sequence of bases in DNA. The four bases (C, A, T/U, and G in the ...

Elongation, a crucial step in the translation process of protein synthesis, gets disrupted by amino acid sequences with an abundance of N-terminal aspartic and glutamic acid residues in eukaryotic ...

Using ribosome engineering (RE), researchers from Shinshu University introduced mutations affecting the protein synthesis ...