The research focused on the addition and removal of a terminal negatively charged sugar modification, called sialic acid, of MUC5B, one of the major mucin proteins found in the airway.

The research focused on the addition and removal of a terminal negatively charged sugar modification, called sialic acid, of MUC5B, one of the major mucin proteins found in the airway.

Discover how sugar modifications, particularly sialic acid, impact mucus formation and transport, contributing to diseases like cystic fibrosis and COPD. The critical role of sugar modifications ...

The research focused on the addition and removal of a terminal negatively charged sugar modification, called sialic acid, of MUC5B, one of the major mucin proteins found in the airway.

Recombinant adeno-associated virus vectors based on serotype 2 (rAAV2) have been used to deliver transgenes to the airways in a variety of pre-clinical and clinical studies. Gene transfer in these ...

Exposure to non-microbial N -Glycolylneuraminic acid protects farmers’ children against airway inflammation and colitis. Journal of Allergy and Clinical Immunology , 2017; DOI: 10.1016/j.jaci ...

The sialic acid-rich antibodies, but not the others, protected the animals from both types of flu, evidently due to markedly reduced lung inflammation. “The reduced inflammation led to better oxygen ...

Cells respond to water and acid "We knew something about what these cells were doing in the lungs, but not the upper airway," said Laura Seeholzer, Ph.D., a UCSF postdoctoral fellow in the Julius ...

The research focused on the addition and removal of a terminal negatively charged sugar modification, called sialic acid, of MUC5B, one of the major mucin proteins found in the airway. A high anionic ...

The research focused on the addition and removal of a terminal negatively charged sugar modification, called sialic acid, of MUC5B, one of the major mucin proteins found in the airway.