Cryo-electron microscopy (cryo-EM) can help scientists determine the three-dimensional structure of proteins in unprecedented ...

In the single-beam FIB, such as our Hitachi FB-2000A FIB, some milling will occur during observation of the specimen. Surface features, such as thin films, can be milled away during this process. In ...

As a surface-sensitive technique, the diffraction signal comes from the top few nanometers of the crystal lattice in EBSD. Hence, the top layer needs to be devoid of oxidation, contamination and ...

The author examines sample-preparations methods used in inductively coupled plasma–optimal emission spectroscopy for four test metals. When analyzing for trace metals using inductively coupled plasma ...

To produce high-quality cement, the mineralogical and chemical composition of raw materials, as well as of intermediate and finished products, needs to be determined. At each stage of the production ...

The family of electron microscopy techniques have become staple methods for imaging nanoscale objects, including nanoparticles, viruses and proteins. The appeal of electron microscopy as a ...

The in situ heating temperature, sputtering power and argon gas pressure are all parameters, which may impact the magnetic properties, microstructure and applicability of these materials for HAMR.

Correlative imaging involves the spatial integration of imaging data collected by different microscopy techniques from a single specimen. Its power relies on its ability to bring together data from ...

Quality control (QC) is a critical step in the pharmaceutical and biopharmaceutical industry. Every manufacturer must demonstrate that its drugs are consistently produced, safe, potent, and pure. The ...

Agilent Technologies Inc. has announced the release of “Sample Preparation Fundamentals for Chromatography,” written by sample preparation expert Ronald E. Majors, Ph.D. The publication is a ...

Although next-generation sequencing (NGS) keeps giving—exploring the human genome and revolutionizing our knowledge of health and disease—it needs to take a little, too. At the very least, NGS ...

The ultramicrotomes are mainly used to prepare thin sections for imaging with TEM. Either glass or diamond knifes can be used to cut thin sections of specimens embedded in epoxy. The section thickness ...