Gene mutations may explain some spontaneous spinal fluid leaks

Researchers at Cedars-Sinai Health Sciences University and Johns Hopkins University have identified genetic mutations that ...
Nanowerk

Mutation: Types, Causes, Effects on Genes and Proteins, and Role in Disease

In simple terms: a mutation is a stable change in genetic sequence that can be copied when cells or viruses replicate. Most mutations have no detectable effect, some contribute to disease, and a small ...
Nature

Mutation Dynamics and Fitness Effects in Evolving Populations

Mutation dynamics and fitness effects lie at the heart of evolutionary change. Every generation, genomes accrue spontaneous alterations ranging from single-nucleotide substitutions to larger ...
News-Medical.Net

Researchers uncover genetic cause of spontaneous spinal CSF leaks

Researchers at Cedars-Sinai Health Sciences University and Johns Hopkins University have identified genetic mutations that may explain why some people develop a spontaneous cerebrospinal fluid (CSF) ...
Technology Networks

Genetic Variants Linked to Spontaneous Cerebrospinal Fluid Leaks

A study linked spontaneous spinal CSF leaks to genetic variants that weaken connective tissue around the spinal cord, ...
Nature

Quantifying the effects of computational filter criteria on the accurate identification of de novo mutations at varying levels of sequencing coverage

The rate of spontaneous (de novo) germline mutation is a key parameter in evolutionary biology, impacting genetic diversity and contributing to the evolution of populations and species. Mutation rates ...