Researchers have engineered a next-generation glutamate sensor, iGluSnFR4, capable of detecting the faintest incoming ...

Your brain doesn t just send messages through one universal route it uses separate pathways for spontaneous activity and signals linked to learning. These findings overturn a major neuroscience ...

Harvard researchers have mapped and catalogued more than 70,000 synaptic connections from about 2,000 rat neurons, using a silicon chip capable of recording small yet telltale synaptic signals from a ...

Parkinson's and Alzheimer's diseases are the two most common neurodegenerative disorders, affecting millions of people worldwide. Published in the Journal of Neuroscience, new research from the ...

Ketamine is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist that produces rapid antidepressant action in some patients with treatment-resistant depression. However, recent data ...

Neurons can rapidly rebalance their communication using a structural signal rather than electrical activity, overturning long-held assumptions about how synapses maintain stability.

Increased levels of bioactive lipids produced naturally in the body, which affect excitatory transmission between brain cells, promote mental disorders. However, this mechanism can be rebalanced by ...

Synaptic pruning is a crucial neurodevelopmental process through which the brain refines its neural circuitry by systematically eliminating excess or weak synaptic connections. During early childhood ...

A) Taste tissue of wild-type mice and taste cell synaptic dysfunction mice (SNAP-cKO). In SNAP-cKO mice, the number of sour-sensing cells is reduced. B) Gustatory nerve responses to various taste ...

Researchers from The University of Texas at Dallas’ Center for Advanced Pain Studies (TX, USA) and their colleagues have made a fundamental discovery about a key mechanism that enables nervous system ...