When Ben Orlando delivered a 2019 research talk at Michigan state University's Department of Biochemistry and Molecular Biology, it set the stage for a collaborative breakthrough that was decades in ...

A collaborative team from the Rosalind Franklin Institute, the University of Oxford, and Diamond Light Source has developed a breakthrough method that makes it possible to image very small proteins ...

In 1977, the Nobel Prize in Physiology or Medicine was awarded to Roger Guillemin and Andrew Schally for their discovery and synthesis of gonadotropin-releasing hormone (GnRH), a key regulator of ...

Transient receptor potential (TRP) ion channels have a crucial role as cellular sensors, mediating diverse physical and chemical stimuli. The formation of heteromeric structures expands the ...

Prof. Liu Cong from the Shanghai Institute of Organic Chemistry of the Chinese Academy of Sciences, along with collaborators, has revealed the high-resolution structures of amyloid fibrils directly ...

On the left is integrase in its “intasome” structure of four identical four-part complexes (pink) that connect to create one 16-part complex that locks around viral DNA (blue). On the right is ...

Toward the goal of efficient editing of farm animals for genetic improvements, this study explores an upgraded form of nuclease PE (uPEn). Based on the resolved structure of the NiV polymerase L-P ...

WEST LAFAYETTE, Ind. — Purdue University experts in the College of Science and Rosen Center for Advanced Computing have launched Molecular Intelligence, a software company whose solutions help ...

Structural biology is used to understand the three-dimensional shape of biological molecules and how their shape enables them to function both inside and outside of cells. Furthermore, the ...

Channelrhodopsins (ChRs) are light-gated ion channels and invaluable tools for optogenetic applications. Recent developments in multicolor optogenetics, in which different neurons are controlled by ...