A newly discovered molecule disrupts cancer cells’ ability to repair DNA by triggering the breakdown of key proteins. Cancer cells can survive by repairing damage to their DNA—even damage that would ...

A news feature on the research paper "Next-generation cell-penetrating antibodies for tumor targeting and RAD51 inhibition" by Rackear et al. was published in Oncotarget's Volume 15 on November 22, ...

Every time a cell divides, its DNA is duplicated so that the two daughter cells have the same genetic material as their parent. This means that millions of times a day a biochemical wonder takes place ...

“A key objective of research focused on early-stage breast cancer is to identify biomarkers that can select patients who might benefit from less aggressive treatments than chemotherapy and personalize ...

Researchers created a mutated version of RAD51, a DNA repair protein, to better understand its critical functions at key steps in the cell replication process during times of stress. This work may ...

Researchers at the Francis Crick Institute have outlined the structure and function of a protein complex that is required to repair damaged DNA and protect against cancer. Using cryo-electron ...

Scientists have revealed an important mechanism in the repair of DNA double-strand breaks, according to new research. Scientists have revealed an important mechanism in the repair of DNA double-strand ...

Cancer cells survive by repairing damage to their DNA—even damage that would normally be fatal. One of their most important ...