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Targeting TGF-β signaling as a strategy to treat liver fibrosis

Liver fibrosis, a pathological scarring process resulting from chronic liver injury, represents a significant global health ...
Kaleido Scope

Murphy-Ullrich Inducted into National Academy of Inventors

Joanne Murphy-Ullrich, Ph.D., Professor Emerita, Molecular and Cellular Pathology, has been inducted into UAB's chapter of the National Academy of Inventors. Murphy-Ullrich was recognized at an ...
mskcc.org

TGF-Beta and RAS Signaling Are Both Required for Lung Cancer Metastasis, Study Finds

A tissue section from a mouse model of lung metastasis showing cancer cells (green) that have attracted and activated fibroblasts (red) to support the growth of a metastatic tumor. Image: Massagué Lab ...
EurekAlert!

Northwestern's cancer genetics program finds gene variants that greatly increase breast cancer risk

CHICAGO – Decreased activity within the Transforming Growth Factor Beta (TGF-beta) pathway is associated with increased breast cancer risk, according to a study published by researchers at ...
Healio

Q&A: Blocking TGF-beta signals may prevent cancer in liver, GI system

Please provide your email address to receive an email when new articles are posted on . Transforming growth factor beta mutation biomarkers may help identify patients at high risk for cancer of the ...
GEN

Response to Immunotherapy Predicted by Extracellular Matrix Genes

Immunotherapy has been a life-saving intervention for an array of diseases, particularly cancer. However, the treatments are not suited for every patient and can lead to serious side effects and even ...
Healio

Q&A: Asporin linked to ‘more favorable disease profile’ in patients with PAH

Please provide your email address to receive an email when new articles are posted on . In PAH lung samples, researchers observed elevated asporin levels and found a link between these levels and ...