The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a ...

Researchers have discovered that mice possess a natural form of gene therapy, a non-coding RNA that can sidestep genetic mutations. They were able to engineer a programmable version that ...

Long non-coding RNAs (lncRNA) are a type of RNA molecule that do not carry instructions to make proteins. Instead, they influence how other genes are expressed. There are tens of thousands of ...

Kim’s lab developed an RNA liquid biopsy platform that detects both protein-coding RNA and RNA dark matter in the blood, and showed that this new approach significantly improves the performance of ...

Their findings, recently published in Nucleic Acids Research, spotlight TERRA—a long non-coding RNA transcribed from the ends of chromosomes—as a potential biomarker for age-related and ...

A liquid biopsy diagnostic that detects noncoding RNA in addition to protein-coding RNA improves early stage cancer diagnosis.

Gene expression is boosted when mRNA anneals with antisense RNA to form double-stranded RNA, which is exported from the nucleus more quickly than single-stranded RNA.

Identification of non-coding regions that control gene expression, like CHASERR, is one way her team is thinking about using their knowledge of the human genome to design gene-targeting therapies.

Splice of life Mutations in a non-coding gene associated with intellectual disability A gene that only makes an RNA is linked to neurodevelopmental problems.

The ability to correct disease-causing genetic mistakes using genome editors holds great promise in medicine, but it is not ...