The San Francisco 49ers picked up their first loss of the season, falling 23-17 to the Minnesota Vikings in Week 2. A special teams error, two turnovers (interception and fumble) and two turnovers ...

The last time the 49ers played a game without Christian McCaffrey and Deebo Samuel, they scored 23 points and lost to the Seahawks. That was back in 2021 when Jimmy Garoppolo was the quarterback ...

The 49ers reportedly checked in on multiple potential replacements for Brandon Aiyuk in the wake of the uncertainty surrounding the wide receiver this offseason. Before San Francisco ended their ...

The San Francisco 49ers take their 1-0 record to the road against the Minnesota Vikings on Sunday. San Francisco easily took care of the Aaron Rodgers and the New York Jets at home in the season ...

The San Francisco 49ers recently navigated a tumultuous period involving wide receiver Brandon Aiyuk, who initially sought a trade but ultimately secured a new contract with the team. The ...

The upcoming clash between the Minnesota Vikings and the San Francisco 49ers at U.S. Bank Stadium marks a crucial early test for the Vikings. As both teams enter the game coming off season-opening ...

Brock Purdy offered Brian Flores the best compliment a coach could ask for. On the field after the 49ers' 23-17 loss to the Minnesota Vikings on Sunday at U.S. Bank Stadium, Purdy was approached ...

The San Francisco 49ers didn't need Christian McCaffrey ... It forced George Kittle to wear Brock Purdy's Cyclones helmet during his media availability on Wednesday. Speaking of Kittle, he ...

MINNEAPOLIS -- The San Francisco 49ers placed star running back Christian McCaffrey on injured reserve with calf soreness and Achilles tendinitis, the team announced Saturday. McCaffrey must miss ...

Amid the offseason uncertainty surrounding Brandon Aiyuk, the 49ers checked in on Justin Jefferson's availability before this year's NFL draft, but the Vikings had zero interest in trading the ...