The San Francisco 49ers will be without the services of one of their top offensive weapons for the foreseeable future.

Suddenly the 49ers have just one healthy running back they trust. Christian McCaffrey has Achilles tendonitis and could go to ...

The San Francisco 49ers will have to make some tough decisions to make after the season about keeping the roster together.

Jimmy Garoppolo knows what it feels like as a San Francisco 49er to come to L.A., but now the quarterback is on the other ...

When RB Blake Corum and the Los Angeles Rams take on the San Francisco 49ers in Week 3 on Sunday at 4:25 PM ET, they will be ...

In Week 3, running back Kyren Williams and the Los Angeles Rams' rushing attack will match up with the San Francisco 49ers ...

The Pittsburgh Steelers are adding a former Texas Longhorns star to their practice squad. The team announced Tuesday the ...

This offseason saw the Vikings sign their young, star wide receiver Justin Jefferson to the biggest contract for a pass ...

For Vikings vs. 49ers, the model is backing San Francisco to cover the spread. Kyle Shanahan's team looked like a repeat ...

Injuries can make or break your fantasy season. Here is the latest news on the NFL's biggest stars with injury questions ...

It took several months, but the 49ers finally signed Brandon Aiyuk to a lucrative contract extension last month. After both sides came to the agreement, multiple reports surfaced about how the ...

Now would be a good time to sign a free agent running back who fits the system just in case Mason goes down, as running backs often do. Fortunately for the 49ers, such a running back is available ...