San Francisco 49ers wide receiver Deebo Samuel will be sidelined the next couple of weeks because of a calf strain he endured ...

Minnesota has been a house of horrors for the San Francisco 49ers for decades. The Niners’ eighth straight loss in the Twin ...

Already without running back Christian McCaffrey, the 49ers are poised to be without wide receiver Deebo Samuel for a couple ...

The Los Angeles Rams are off to their first 0-2 start to a season since Les Snead became their general manager 12 years ago.

When Christian McCaffrey went down, the 49ers could take solace in the fact that they had another versatile and dynamic ...

The San Francisco 49ers are dealing with another notable injury. The 49ers, who recently put All-Pro running back Christian ...

Get live streaming info, TV channel, game time, and head-to-head stats for the San Francisco 49ers vs. Los Angeles Rams week ...

An NFL referee in Sunday's 49ers vs. Vikings game wowed fans with his speed during Justin Jefferson's 97-yard touchdown catch ...

Get live streaming info, TV channel, game time, and head-to-head stats for the Los Angeles Rams vs. San Francisco 49ers week ...

Here's where the San Francisco 49ers and the rest of the NFL stand in the latest power rankings heading into Week 3.

Ask teammates about McCaffrey and many will compare his "gravity" to that of Golden State Warriors guard Stephen Curry. The ...

Sunday was another relatively light outing for the San Francisco 49ers defense, which logged 54 snaps after getting just 51 ...