Understanding the signal transduction pathways involved in the differentiation process is vital to the success of this approach. GLP-1—a hormone secreted by the L cells of the small intestine ...

effects that suggest that increasing central GLP-1 signaling could reduce cocaine seeking. Further investigation pinpointed a specific brain circuit: GLP-1-producing neurons in the nucleus tractus ...

BRP, identified through peptide prediction, may revolutionize weight loss treatment, offering efficacy without the ...

Similar to other inhibitors of the activin signaling pathway, animal and clinical studies have shown that bimagrumab can increase muscle mass and lean body mass. The use of GLP-1 receptor agonists ...

GLP-1 drugs also improve blood flow to the ... as well as the restoration of brain pathways of insulin signaling that may lead to improved memory formation and therefore a positive effect in ...

"We know that reducing insulin, and reducing IGF signaling, slows aging and extends ... and glucagon-like peptide-1 (GLP-1).

"We believe the data from this study will demonstrate that the combination of MC4R + GLP-1/GIP agonists ... with GLP-1 and GIP drugs," continued Dr. Spana. "The MC4R pathway plays a key role ...