The research focused on the addition and removal of a terminal negatively charged sugar modification, called sialic acid, of MUC5B, one of the major mucin proteins found in the airway.

Discover how sugar modifications, particularly sialic acid, impact mucus formation and transport, contributing to diseases like cystic fibrosis and COPD. The critical role of sugar modifications ...

The sialic acid-rich antibodies, but not the others, protected the animals from both types of flu, evidently due to markedly reduced lung inflammation. “The reduced inflammation led to better oxygen ...

The research focused on the addition and removal of a terminal negatively charged sugar modification, called sialic acid, of MUC5B, one of the major mucin proteins found in the airway.

Recombinant adeno-associated virus vectors based on serotype 2 (rAAV2) have been used to deliver transgenes to the airways in a variety of pre-clinical and clinical studies. Gene transfer in these ...

The research focused on the addition and removal of a terminal negatively charged sugar modification, called sialic acid, of MUC5B, one of the major mucin proteins found in the airway.

Cells respond to water and acid "We knew something about what these cells were doing in the lungs, but not the upper airway," said Laura Seeholzer, Ph.D., a UCSF postdoctoral fellow in the Julius ...

Neuroendocrine cells in the larynx and trachea, which make up the passageway from the mouth to the lungs, can sense water and acid passing through, a team reports in the April 19 Science.

CPAM or congenital pulmonary airway malformation (a lobe of the lung is a non-working piece of abnormal lung tissue) Pulmonary emphysema (congenital) Tracheomalacia (when the airway is too soft or ...

The research focused on the addition and removal of a terminal negatively charged sugar modification, called sialic acid, of MUC5B, one of the major mucin proteins found in the airway. A high anionic ...

The research focused on the addition and removal of a terminal negatively charged sugar modification, called sialic acid, of MUC5B, one of the major mucin proteins found in the airway.