Christina Applegate and Jamie-Lynn Sigler discuss differences in how they live with multiple sclerosis in an emotional ...

The Sopranos' actress says her own experience coping with MS has helped with her 11-year-old son's remarkable recovery from a rare autoimmune condition Jamie-Lynn Sigler's 11-year-old son Beau was ...

“I just didn’t know what that would mean for me to say it out loud and have everybody know,” Jamie-Lynn Sigler says in PEOPLE’s exclusive clip of her and Christina Applegate’s new ...

Jamie-Lynn Sigler’s 10-Year-Old Son Beau Leaves Hospital 33 Days After ‘Nightmare’ Diagnosis Jamie-Lynn Sigler Reveals Son Beau Has Been Diagnosed with Autoimmune Disorder After Catching a ...

In a heartfelt conversation on Hoda Kotb's Making Space podcast, Christina Applegate and Jamie-Lynn Sigler opened up about ...

Jamie-Lynn Sigler is going up against her Sopranos brother, Robert Iler, on The $100,000 Pyramid! In PEOPLE's exclusive look at the March 23 episode of the game show, the two former costars ...

31,281 people played the daily Crossword recently. Can you solve it faster than others?31,281 people played the daily Crossword recently. Can you solve it faster than others?

Applegate revealed in an episode of the podcast "MeSsy," which she co-hosts with fellow actress Jamie-Lynn Sigler, that she's been in and out of urgent care constantly since being diagnosed with ...

“For three years, since I was diagnosed I’ve been in the hospital upwards of 30 times from throwing up and diarrhea and pain,” the 53-year-old revealed on her and Jamie-Lynn Sigler’s ...

Christina Applegate is letting fans in on some of the details of her struggle against MS over the past three years.

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