Louisville's defense got off to a very good start in Death Valley, forcing Clemson to go three-and-out on their first two drives of the night. While their offense struggled some to get things going right out of the gates, the Cardinals did strike first, connecting on a 21-yard field goal on their second drive of the game.

Isaac Brown rushed for 151 yards, including a game-sealing 45-yard touchdown burst with 5:50 to play, as Louisville went to Clemson and stunned the No. 11 Tigers 33-21 in the

But tonight that weight has finally lifted with a 33-21 drubbing of the #11 Clemson Tigers on the road, at night, in Death Valley. And it wasn’t even that close. And Clemson’s College Football Playoff hopes are all but dashed.