The Securities and Exchange Commission will assess how a regulatory proposal expanding the definition of an exchange can be modified to exclude entities that facilitate crypto transactions, Acting SEC ...

These new mutation sites are quite conserved across several different species (Figure 2C). Table 1. Bi-allelic DNAH3 variants identified in OAT men. 3.2 DNAH3 is testicle-specific and closely related ...

Here we describe 5 patients from 2 unrelated kindreds with bi-allelic mutations in IRAK4, where one of which was a missense mutation, resulting in a severe autoinflammatory phenotype without overt ...

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However, we still lack understanding of their evolutionary history: the extent of parallelism in the origins of target-site resistance (TSR), how long these mutations persist, how quickly they spread, ...

This strategy centers on the measurement and modeling of ‘allelic manifolds’, a multidimensional generalization of the classical genetics concept of allelic series. Allelic manifolds are measured ...