Recent evidence suggests that multiple sclerosis also affects neurons, as cortical atrophy is detected early in the disease, axon transection can occur in inflammatory lesions, and axonal loss is ...

Voltage-gated sodium channels can contribute to axonal injury in multiple sclerosis (MS ... and they prevent axon degeneration, maintain impulse conduction, and improve clinical status in ...

and multiple sclerosis. The three best examples of ion channel/receptor clustering in the nervous system are found at the synapse, the node of Ranvier, and the axon initial segment (AIS). In the case ...