LOX depletion in SMCs did not influence systolic blood pressures during AngII infusion. Histological analyses indicated increased elastin breaks in SMC-LOX deficiency mice compared to control mice.

Overall, these mice will provide a powerful tool to researchers to study gene function in vascular development/disease by using cre/lox technology to direct smooth muscle–specific gene activation or ...

This small reduction in adipose tissue GLUT4 did not alter the phenotype of Lox/Lox mice relative to that of wild-type or MCK-Cre mice. Nonetheless, we included Lox/Lox mice as controls in all ...

An analytical approach increases spatiotemporal resolution, optimizes real-time, in vivo detection of Met- and Leu-enkephalin, and provides novel insight into the relationship between Met- and ...

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To generate a null allele Plk1 (Δ), Plk1 (lox/lox) mice were crossed with mice carrying RERT2 allele, which includes a tamoxifen‐inducible Cre recombinase ubiquitously expressed under the regulatory ...